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KMID : 0985520120170010044
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Korean Journal of Pancreas and Biliary Tract
2012 Volume.17 No. 1 p.44 ~ p.46
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Immunoglobulin G4-associated Sclerosing Cholangitis Mimicking Hilar Cholangiocarcinoma
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Jang Ji-Woong
Kim Myung-Hwan
Kim Tae-Gyoon
Park Do-Hyun
Lee Sang-Soo
Seo Dong-Wan
Lee Sung-Koo
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Abstract
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Immunoglobulin G4 (IgG4)-associated sclerosing cholangitis is a steroid responsive biliary disease, frequently involving the bile duct, that is often associated with autoimmune pancreatitis. It is characterized by elevation of immunoglobulin G4 in serum and infiltration of immunoglobulin G4 positive plasma cells in bile ducts. The clinically important thing is to differentiate this rare disease from primary sclerosing cholangitis and cholangiocarcinoma. However, the preoperative diagnosis is likely to be missed due to the lack of specific symptoms and specific imaging features. Therefore, making an early diagnosis requires a high index of suspicion. This article reports on a 71-year-old man with IgG4-associated sclerosing cholangitis mimicking hilar cholangiocarcinoma.
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KEYWORD
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Immunoglobulin G4, Sclerosing cholangitis, Cholangiocarcinoma, Autoimmune pancreatitis
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